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Verity Software House mod fit lt cell cycle analysis software
Mod Fit Lt Cell Cycle Analysis Software, supplied by Verity Software House, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mod+fit+lt+software/analysis+cell+cycle+modfit+software/pmc12366417-225-51-58
Average 86 stars, based on 1 article reviews
mod fit lt cell cycle analysis software - by Bioz Stars, 2026-09
86/100 stars

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Staining:

Article Title: Synthesis of 5-hydroxyisatin thiosemicarbazones, spectroscopic investigation, protein-ligand docking, and in vitro anticancer activity.
Article Snippet: A series of novel modifications were performed at the N(4) position of 5-hydroxyisatin thiosemicarbazone (TSC).. The structure–activity approach is applied to design and synthesize derivatives by condensing thiosemicarbazides with 5-hydroxy isatin.. The TSCs were characterized by various spectroscopic techniques viz.

Article Title: Panepoxydone Targets NF-kB and FOXM1 to Inhibit Proliferation, Induce Apoptosis and Reverse Epithelial to Mesenchymal Transition in Breast Cancer
Article Snippet: .. After 24 hrs cells were fixed in methanol, stained with Popidium iodide/RNase binding buffer for 30 min at 37°C and analyzed by using flow cytometry on a BD-FACS CantoTM II (Becton-Dickinson, San Jose, CA) to calculate the percentage of cell population in various phases of cell cycle using Mod Fit LT software (Verity Software House, Topsham, ME). ..

Flow Cytometry:

Article Title: Synthesis of 5-hydroxyisatin thiosemicarbazones, spectroscopic investigation, protein-ligand docking, and in vitro anticancer activity.
Article Snippet: A series of novel modifications were performed at the N(4) position of 5-hydroxyisatin thiosemicarbazone (TSC).. The structure–activity approach is applied to design and synthesize derivatives by condensing thiosemicarbazides with 5-hydroxy isatin.. The TSCs were characterized by various spectroscopic techniques viz.

Article Title: Panepoxydone Targets NF-kB and FOXM1 to Inhibit Proliferation, Induce Apoptosis and Reverse Epithelial to Mesenchymal Transition in Breast Cancer
Article Snippet: .. After 24 hrs cells were fixed in methanol, stained with Popidium iodide/RNase binding buffer for 30 min at 37°C and analyzed by using flow cytometry on a BD-FACS CantoTM II (Becton-Dickinson, San Jose, CA) to calculate the percentage of cell population in various phases of cell cycle using Mod Fit LT software (Verity Software House, Topsham, ME). ..

Article Title: 5-Methoxyisatin N(4)-Pyrrolidinyl Thiosemicarbazone (MeOIstPyrd) Restores Mutant p53 and Inhibits the Growth of Skin Cancer Cells, In Vitro
Article Snippet: .. The cells were acquired using a BD FACSverse flow cytometer and analyzed by MoD Fit LT software (Verity Software House, USA). ..

Article Title: Combination of metformin/efavirenz/fluoxetine exhibits profound anticancer activity via a cancer cell-specific ROS amplification
Article Snippet: .. After washing twice with PBS, the fixed cells were collected by centrifugation at 850 g. RNase A (ThermoFisher, DNase and protease-free) at 50 μl (100 μg/ml) was added to the cells and incubated for 30 min. Propidium iodide (Merck Millipore, P4170) at 200 μl (50 μg/ml) was added to the cells, and the cell cycle was analyzed using a flow cytometer (Becton Dickinson, Vantage SE cell sorter) and a mod Fit LT software (Verity Software, Topsham, ME). ..

Software:

Article Title: Synthesis of 5-hydroxyisatin thiosemicarbazones, spectroscopic investigation, protein-ligand docking, and in vitro anticancer activity.
Article Snippet: A series of novel modifications were performed at the N(4) position of 5-hydroxyisatin thiosemicarbazone (TSC).. The structure–activity approach is applied to design and synthesize derivatives by condensing thiosemicarbazides with 5-hydroxy isatin.. The TSCs were characterized by various spectroscopic techniques viz.

Article Title: Panepoxydone Targets NF-kB and FOXM1 to Inhibit Proliferation, Induce Apoptosis and Reverse Epithelial to Mesenchymal Transition in Breast Cancer
Article Snippet: .. After 24 hrs cells were fixed in methanol, stained with Popidium iodide/RNase binding buffer for 30 min at 37°C and analyzed by using flow cytometry on a BD-FACS CantoTM II (Becton-Dickinson, San Jose, CA) to calculate the percentage of cell population in various phases of cell cycle using Mod Fit LT software (Verity Software House, Topsham, ME). ..

Article Title: Panepoxydone Targets NF-kB and FOXM1 to Inhibit Proliferation, Induce Apoptosis and Reverse Epithelial to Mesenchymal Transition in Breast Cancer
Article Snippet: .. Percentage of cell population in apoptosis was calculated using Mod Fit LT software (Verity Software House, Topsham, ME). ..

Article Title: 5-Methoxyisatin N(4)-Pyrrolidinyl Thiosemicarbazone (MeOIstPyrd) Restores Mutant p53 and Inhibits the Growth of Skin Cancer Cells, In Vitro
Article Snippet: .. The cells were acquired using a BD FACSverse flow cytometer and analyzed by MoD Fit LT software (Verity Software House, USA). ..

Article Title: Role of p53 mutation in the effect of boron neutron capture therapy on oral squamous cell carcinoma
Article Snippet: Thereafter, the cells were washed twice with ice-cold PBS and treated with 1 mg/ml RNase at 37°C for 30 min. After staining of cellular DNA with 50 μg/ml propidium iodide in PBS, cells were analyzed with a fluorescence-activated cell sorter (FACSort; Becton Dickinson, Mountain View, CA). .. The percentage of cells at different phases of the cell cycle was determined by employing Mod Fit LT software (Verity Software House, Topsham, ME). ..

Article Title: Activation of p38MAPK Contributes to Expanded Polyglutamine-Induced Cytotoxicity
Article Snippet: DNA content was analyzed by flow cytometry using a BD LSR flow cytometer (Becton Dickinson, San Jose, CA). .. Data was acquired using Cell Quest software (Becton Dickinson, San Jose, CA) and were analyzed using Mod Fit LT software (Verity Software House, Inc., Sopsham, ME). ..

Article Title: Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies.
Article Snippet: Co-inhibition of histone deacetylase (HDAC) and cyclin-dependent kinase (CDK) synergizes to produce enhanced antitumor effects and potentially overcomes the drug resistance.. In this work, we discovered a series of novel CDK9/HDACs dual inhibitors.. Among them, compound 8e was identified to show potent CDK9 and HDAC1 inhibitory activities, with IC50 values at 88.4 and 168.9 nM, respectively, and exhibited antiproliferative capacities against hematological and solid tumor cells.

Article Title: Combination of metformin/efavirenz/fluoxetine exhibits profound anticancer activity via a cancer cell-specific ROS amplification
Article Snippet: .. After washing twice with PBS, the fixed cells were collected by centrifugation at 850 g. RNase A (ThermoFisher, DNase and protease-free) at 50 μl (100 μg/ml) was added to the cells and incubated for 30 min. Propidium iodide (Merck Millipore, P4170) at 200 μl (50 μg/ml) was added to the cells, and the cell cycle was analyzed using a flow cytometer (Becton Dickinson, Vantage SE cell sorter) and a mod Fit LT software (Verity Software, Topsham, ME). ..

Binding Assay:

Article Title: Panepoxydone Targets NF-kB and FOXM1 to Inhibit Proliferation, Induce Apoptosis and Reverse Epithelial to Mesenchymal Transition in Breast Cancer
Article Snippet: .. After 24 hrs cells were fixed in methanol, stained with Popidium iodide/RNase binding buffer for 30 min at 37°C and analyzed by using flow cytometry on a BD-FACS CantoTM II (Becton-Dickinson, San Jose, CA) to calculate the percentage of cell population in various phases of cell cycle using Mod Fit LT software (Verity Software House, Topsham, ME). ..

Centrifugation:

Article Title: Combination of metformin/efavirenz/fluoxetine exhibits profound anticancer activity via a cancer cell-specific ROS amplification
Article Snippet: .. After washing twice with PBS, the fixed cells were collected by centrifugation at 850 g. RNase A (ThermoFisher, DNase and protease-free) at 50 μl (100 μg/ml) was added to the cells and incubated for 30 min. Propidium iodide (Merck Millipore, P4170) at 200 μl (50 μg/ml) was added to the cells, and the cell cycle was analyzed using a flow cytometer (Becton Dickinson, Vantage SE cell sorter) and a mod Fit LT software (Verity Software, Topsham, ME). ..

Incubation:

Article Title: Combination of metformin/efavirenz/fluoxetine exhibits profound anticancer activity via a cancer cell-specific ROS amplification
Article Snippet: .. After washing twice with PBS, the fixed cells were collected by centrifugation at 850 g. RNase A (ThermoFisher, DNase and protease-free) at 50 μl (100 μg/ml) was added to the cells and incubated for 30 min. Propidium iodide (Merck Millipore, P4170) at 200 μl (50 μg/ml) was added to the cells, and the cell cycle was analyzed using a flow cytometer (Becton Dickinson, Vantage SE cell sorter) and a mod Fit LT software (Verity Software, Topsham, ME). ..



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